pneumoniae pneumonia are rarely obtained. Therefore pathological specimens of human M. An estimated 3–13% of infected persons with infection experience pneumonia, and the remains are manifested as upper respiratory tract infection. The majority of Mycoplasma (M) pneumoniae respiratory infection are self-limited. pneumoniae pneumonia may be altered by the level of host CMI. It was suggested the pathological features of M. From these findings, up-regulation of host CMI could change radiological pattern to centrilobular nodules predominant, on the other hand down-regulation of host CMI would change radiological pattern to ground-glass opacity and consolidation. Patients with centrilobular nodules predominant radiologic pattern have a high level of CMI, measuring by tuberculin skin test. pulmonis-infected mice model, pathologic patterns are strikingly different according to host cell-mediated immunity (CMI) levels treatment with interleukin-2 lead to marked cellular bronchitis in the small airways and treatment with prednisolone or cyclosporin-A lead to neutrophils and exudates in the alveolar lumen. (3) Neutrophils and exudates in the alveolar lumen radiologically demonstrated as air-space consolidation or ground-glass opacities. ![]() (2) Cellular bronchitis in the small airways accompanied with exudates or granulation tissue in the lumen revealed as centrilobular nodules on CT. (1) Peribronchial and perivascular cuffing characterized by mononuclear cells infiltration was correlated with bronchovascular bundles thickening on CT, which was the most common finding of this pneumonia. Major three correlations were summarized. Therefore, we extensively reviewed the literature regarding pathological and radiological studies of Mycoplasma pneumonia, and compared findings between open lung biopsy specimen and computed tomography (CT). pneumoniae pneumonia are often difficult to recognize on radiography but can usually be seen on high-resolution CT.Studies focused on the pathological–radiological correlation of human Mycoplasma ( M) pneumoniae pneumonia have rarely been reported. The lobular distribution, centrilobular involvement, and interstitial abnormalities in M. Thickening of the bronchovascular bundles was identified more commonly on CT (23 of 28 patients, 82%) than on radiography (five patients, 18%) (p < 0.01, chi-square test). In 24 (86%) of the 28 patients, the nodules had a predominantly centrilobular distribution on CT. Nodules were seen more commonly on high-resolution CT (25 of 28 patients, 89%) than on radiography (14 patients, 50%) (p < 0.01, chi-square test). In 13 patients (59%), the areas of consolidation had a lobular distribution evident on CT. On high-resolution CT, areas of ground-glass attenuation were seen in 24 patients (86%) and air-space consolidation in 22 (79%). The most common finding on radiography was the presence of air-space opacification (n = 24), which was patchy and segmental (n = 9) or nonsegmental (n = 15) in distribution. The radiographs and CT scans were analyzed independently by two observers. ![]() ![]() pneumoniae pneumonia were retrospectively reviewed. The chest radiographs and 1.5-mm collimation CT scans obtained in 28 patients with serologically proven M. The aim of the study was to compare the radiographic and the high-resolution CT findings of Mycoplasma pneumoniae pneumonia.
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